Nope, no real discomfort. Just normal fatigue and some mild soreness after particularly heavy days. I’m up to squatting sets of about 1.5x body weight, and deadlifting almost 2x, so warming up takes a while.

Honestly, my knees and ankles feel more after running than after lifting. It’s part of the reason why I switched emphasis from running to lifting. I used to run a lot, but nagging injuries caused me to step back about 10 years ago.