Want to be evil but too lazy to get out there? Too afraid you might get caught? What if I told you that you could participate in a group effort to kill people? And all you have to do is sit back, enjoy yourself, and burn that energy! Between 2000–2019 studies show approximately 489,000 heat-related deaths occur each year! That’s right! All you need to do to contribute to the death of humans is pump up that global warming! So blast that heater in the winter, your AC in the summer, and eat as much meat as you like! Sure, it might be a bit pricy, but that’s what work is for! And don’t forget the workplace can encourage death too! You can rest easy knowing those old, usless fogeys and those noisy babies will be the first to go with the ensuing heatwaves! If you come into a large chunk of money, consider opening a gas station! There, you can peddle ciggarettes and nicotine, alcohol depending on your state, and don’t forget those sweet, sweet, (corn syrupy sweet!) fountain sodas that contribute towards the obesity epidemic! Plus you get to fuel cars that pump more carbon into the air and support the oil industries that pollute the environment! Remember, there’s always plenty of legal ways to contribute to human deaths! So relax and do your part, and remember, humanity likely won’t kill all life, as it’s rather tenacious. But we can certainly make this planet inhospitable enough that the humans’ll all die off! And that’s the goal!

The issue with prions is they’re not that contagious. An infected person is not a danger to other people. This means you need to contaminate all the meat in the food supply because you can’t rely on transmission.

No ones been evil enough to think of it. Till now!

Anyone making a bio weapon would go after a virus or fungus. Easier to cultivate, dispurse, and work with. Something that’s contagious and self replicating makes it much easier to hide the initial infection point.

it can take years to see any effect, if at all. PRION cases are very rare. you would need to source the prions from somewhere, its usually from infected nervous tissue or animals with the disease. your better of using an actual infectious agent like a deadly food poisoning bacteria.

Pretty sure that same person would need to also be suicidal as exposure would also infect them. I’m not a microbiologist but from what I understand, they are pretty resilient to everything that would destroy anything by else and even a slight accident exposure and you’re screwed.

Just spent my dinner reading about prion diseases. Huh turns out if I had the genetic fatal insomnia, it’d start showing signs in the next few years.

Might get off the Internet for a while.

If you wanted to go dowm that route of thinking then careful application of money toward long-term political movements would yield better results.

Luckily thats totally in the real of science fiction.

In addition to the other answers here, the incubation period for prion diseases is quite long. Based on a quick search they seem to take anywhere from five to 40 years to even start showing symptoms. A killer would probably want more immediate results.

Why use something so hard to contain and infect people with? Ricin is easier to obtain and works super fast. Dump a bunch in the water table and take out entite cities.