I no longer get excited about medical innovation because I know I’ll never be able to afford to benefit from any of it. I’m lucky to have gotten vaccinated as a child while that was still legal for the poors
When I was a teenager it was announced that we would soon be able to stimulate the growth of brand new teeth, right in the mouth. I’m almost 50 and I need some new fuckin’ teeth real soon.
There was a new development in japan less than a year ago. Downside is all your teeth fall out and all regrow
I’m sorry, I thought you said there was a downside.
You think teething and a soft food diet isn’t a downside? Any time I have anything done that requires soft food, I’m craving solid food within like three days. It sucks.
Given the state of my teeth, I’m not far from that anyway.
It didn’t sound like a big deal, but somehow you just instilled in me an existential dread of having no teeth to enjoy solid foods when craving some.
Well you can still cut it into small pieces for minimal chewing. Last time I couldn’t have solid food at all.
Tooth fairy isn’t unionized.
She’s ionized?
The problem is those new teeth were soft with no enamel. This could address that. Either way, no insurance will cover this and it will cost a fortune.
My teeth already have no enamel so I’m game.
its possible now but the world is pretty fucked. we can already reduce aging too and reverse it, we have cancer treatments that have near 100 percent success rates for many cancers, and many of these developments were only in recent years but when you watch how much gets done without making it into actual hospitals because of shitass companies and practices it makes you feel a little concerned if any of that will really have an impact, especially when everything is already burning anyway…
No offense, but unless you have some sort of condition like not growing enamel, what have you been doing for your teeth to be that bad at not even 50? Chewing on anvils and flossing with barbed wire?
Bruxism. Why, what’s wrong with you? Sheesh.
Chemo, Bruxism, Shitty genetics, mental health often leads to poor hygiene, sports or injuries can fuck you.
Bigger question is why you’re choosing to be an A-grade arsehole over it.
Playing hockey?
If this is legit and dental industry doesn’t try to drown it in a bathtub I’ll be fucking shocked.
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Just ignore all those famous exceptions.
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When you zoom out, the invariant story of capitalism is exactly the opposite. Capitalism contains the seeds of its own destruction.
Hell yeah. I’m gonna overuse this shit and just have 2 gigantic teeth. One on the top and one on the bottom. No more flossing for me. Fuse those bad boys together. I’ll have the smile of an N64 game character.
Currently sitting in an Uber relying on autocorrect to spell for me. I don’t want to belly laugh and make my driver think I’m a crazy person fuk u
Gotta get that cartoon chin as well.
if you’re gonna get chin work, make sure you have a butt chin (with a smaller, extendable butt implant installed in the cleft)
Settle down Mitch Hedberg.
I think that’s just called dentures
The researchers used extracted human molars as an ex vivo model, first etching their enamel or dentine surfaces with acid to mimic different stages of tooth erosion. They then applied a single coating of the biomimetic elastin-like recombinamer (ELR) gel and let it dry. Finally, the teeth were immersed in carefully controlled mineralization baths that replicated the ionic environment of saliva.
Keep in mind this hasn’t been shown to actually help teeth in someone’s mouth.
Just from that, it seems like its a patch job, not capable of regrowing from zero.
i wouldn’t expect that from a gel
I definitely saw lots of ads on AliExpress for gels that would regrow your teeth before their algorithm realized I wasn’t there for that.
To be fair, the research is on regenerating, not regrowing. I wouldn’t expect regrowing lost teeth to be possible any time soon, unless some kind of bio 3D-printing method became available.
My guess is that they can slowly regrow lost enamel under fillings, slowly build back up later by layer until a filling is no longer needed. What would be amazing is a cure for gum disease.
How many times have I read this headline…
Every time you read it it’s in a mouse or a petri dish.
I wish they would put that on the headline.
According to the article, they used human teeth from cadavers
There’s a big difference between doing something in a lab and mass producing it for millions of people.
My only question is - when will it be available?
Our medical knowledge is shockingly rudimentary. Why we can’t coax cells to do what they did anyway before is something we really need to understand to pretend to have any kind of medical knowledge. What passes for medicine is nothing more than 19th century++. See this, do that, body will heal. That’s about it. I’m shocked every time I see someone in a wheelchair, how can we have LLMs and hallucinated movies but not understand how a few milligrams of organic matter organizes into nerves? etc etc etc
I am hoping that the absolutely bonkers computing power we are currently wasting on fart videos will be used to simulate matter in the future, here’s to cheering on the AI crash!
We have a pretty good idea how things work during development, it’s tricking those cells into the same process as a fully-formed organism that’s hard. Isolating and distributing the hormones in the right way. I think you’re underselling the complexity and scale of biology. We can’t just put a tiny camera and chemo-sensor inside a neuron and see what’s going on in real time and synthesize up a hundred thousand copies.
That’s my point, we’ll simulate it.
In reality, AI will help solve a lot of our medical ignorance. Not the goofball LLMs, but specialized AI algorithms specifically geared towards niche medical research and applications. Don’t let GPT and Gemini sour the potential of some possibly game changing software.
we do have the ability to coax cells and even turn differenciated cells into pluripotent stem cells we’ve been able to for years the people who did it won a nobel peace prize
The human body is an immensely complex system of chemical reactions.
And before you say “simulate it”, we don’t have nearly enough computational resources to do that. Simple reactions or chains of reactions, yes, but even a simple body process consists of multiple steps and a number of large, complex molecules.
This right here. We can definitely model how a single chemical effects cells, but what about multiple chemicals together. The reality is we are still very far from simulating something like the side effects from multiple interacting drugs at once.
We will likely discover some incredible insights when we do this though.
How long until the dental restoration industry lobbies it out to be banned, so they can keep selling their photoshop jobs of people smiling with new teeth alongside crowns and implants, all at an inflated price?
It already happens with nano-hydroxyapatite pastes. In Europe you find them at the supermarket for 5 euro, in USA you need a prescription and it’s sold for $$$
Uh no. You can get nHA toothpaste in the USA without a prescription, not sure why you’d think that. It’s just not a popular item here so it’s not sold at brick and mortar stores for the most part, though some smaller stores have it. But I have no problem ordering the stuff online.
Proudly “fluoride free” too, which makes me immediately doubt the veracity of their dental health claims.
Maybe it changed in the recent years? I remember clearly it was forbidden by FDA for sale without prescription
Can they make one to generate beaver enamel? I will accept the red color if I can chew through a tree.
beaver have a different composition, its made of iron compounds, i dont think human mouths are adapted to have iron teeth, it might damage your other teeth, because iron is much harder than calcium hydroxyapatite.
there are times i think about getting titanium caps, but my one crown does not feel great and i don’t like how mouthpieces feel
Hopefully in the right place.
Congrats, you’re now a narwhal
Narwhals, narwhals, swimming in the ocean
Causing a commotion 'cause they are so awesome
Behold my new chitinous armour plates!
Don’t give the military ideas like that.
Side effects: sharp fangs and uncontrollable drooling.
Win win
I bet the catch here is it could accidentally grow anywhere in the body as long as it mimics what our mouth has (saliva). Imagine growing enamel in our tongues or throat.
Doesn’t matter without an anchor point
gimmie
I’ve heard about something like this back in 90s for the first time. I guess we won’t see anything ever. Big tooth won’t allow it 😂
isnt that why naHp DOES already in a dental setting/implant, but there hasnt been definitive studies where its conclusive with OTC usage, eventhough there are tons of nahp products out there already from 5-10% with extremely questionable concentration and efficacy as manufactors, often from asia, dont tell thier process of making the toothpastes, and the true concentrations(Davids hide thier ingredients and process so be warned, also it tends to be highly abrasive). i have used some, i noticed most of them are just whitening toothpaste(hence the placebo effect), or overly saturated mint.
You’re telling me I’ve been brushing twice a day all my life for nothing?
Man, what a bummer.
